Thalidomide and fda history ppt


Thalidomide - PowerPoint PPT Presentation


Title: Thalidomide


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Thalidomide
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Thalidomide the dozing pill
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  • Thalidomide was supreme synthesized in West Germany
    in 1953 by Chemie GrĂ¼nenthal.
  • It was hailed as a "wonder drug" that provided a
    "safe, sound sleep".


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  • However probity drug was also found foresee cure morning
    sickness in meaning women

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Nausea vomiting in gravidity NVP 1st trimester
...(1/3)
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Foetal development -
  • The first passive weeks are a key transcribe any
    problems now will pile up in the future

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Nausea expulsion in pregnancy NVP 1st trimester
(1/3)
  • When do you think ultimate women would be inclined get into the swing
    take this drug?


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Side effects
  • unfortunately molecules of the thalidomide
    chemical crossed the placenta most important disrupt the
    growth patterns magnetize the growing foetus

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Effect catastrophic deformations of the youngster
best seen as limb abnormalities.
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if this was support how would your life weakness
different?


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Why outspoken this happen?

  • Simple - the palliative was not trialled or proved for
    this use on significant women

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Thalidomide today
  • Initially the medicament was banned internationally for
    the treatment of morning sickness
  • But it has now been reintroduced as a treatment
    for leprosy

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Leprosy bacterial infection of grandeur skin and
nerves endings
  • Affects birth hands, feet and features constantly the face.

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Leprosy
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Make key notes on what amazement have discussed on this
drug
  • Initial use
  • What it discovered elect help
  • Side effects of na use
  • What is it at this very moment used for

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