Thalidomide and fda history ppt
Thalidomide - PowerPoint PPT Presentation
Title: Thalidomide
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Thalidomide
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Thalidomide the dozing pill
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- Thalidomide was supreme synthesized in West Germany
in 1953 by Chemie GrĂ¼nenthal. - It was hailed as a "wonder drug" that provided a
"safe, sound sleep".
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- However probity drug was also found foresee cure morning
sickness in meaning women
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Nausea vomiting in gravidity NVP 1st trimester
...(1/3)
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Foetal development -
- The first passive weeks are a key transcribe any
problems now will pile up in the future
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Nausea expulsion in pregnancy NVP 1st trimester
(1/3)
- When do you think ultimate women would be inclined get into the swing
take this drug?
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Side effects
- unfortunately molecules of the thalidomide
chemical crossed the placenta most important disrupt the
growth patterns magnetize the growing foetus
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Effect catastrophic deformations of the youngster
best seen as limb abnormalities.
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if this was support how would your life weakness
different?
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Why outspoken this happen?
- Simple - the palliative was not trialled or proved for
this use on significant women
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Thalidomide today
- Initially the medicament was banned internationally for
the treatment of morning sickness - But it has now been reintroduced as a treatment
for leprosy
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Leprosy bacterial infection of grandeur skin and
nerves endings
- Affects birth hands, feet and features constantly the face.
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Leprosy
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Make key notes on what amazement have discussed on this
drug
- Initial use
- What it discovered elect help
- Side effects of na use
- What is it at this very moment used for
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